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Channel: DR ANTHONY MELVIN CRASTO Ph.D – New Drug Approvals
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Ivermectin

IVERMECTIN MK933 22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b 70288-86-7  71827-03-7   C95H146O28 Molecular Weight: 1736.15894 g/mol   C48H74O14, 875.09 Ivermectin is a macrocyclic...

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TRAMADOL

  2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Tramadol (marketed as Ultram, and as generics) is an opioid pain medication used to treat moderate to moderately severepain.[1] When taken...

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GSK 2251052, Epetraborole, AN3365

(S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)-1-hydroxy-1,3-dihydro- 2,1-benzoxaborole (GSK2251052) is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase, and that has been...

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крисаборол , كريسابورول , Crisaborole, AN 2728

  Crisaborole Treatment for Inflammatory Skin Diseases, including Atopic Dermatitis and Psoriasis C14H10BNO3, Average mass251.045 Da 4-[(1-Hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile ,...

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FDA Says Chinese Pfizer Plant Hid Failures, Used Old Ingredients

Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: October 31, 2015 — 2:22 AM IST, The Pfizer Ltd. research and development plant in Dalian, China. Bernardo De Niz/Bloomberg A Pfizer Inc....

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AN-2718, a New Borole in the pipeline

AN-2718, 2,1-Benzoxaborole, 5-chloro-1,3-dihydro-1-hydroxy- 5-chloro-1,3-dihydro-l-hydroxy-2,1- benzoxaborole 5-Chloro-2,1-benzoxaborol-1(3H)-ol CAS 174672-06-1 UNII: 810U6C2DGG MW 168.3864, MF C7 H6...

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SOFOSBUVIR HPLC

SEE           http://www.google.co.in/patents/US20100298257 Example 28 Chemical Purity Determination by HPLC Various HPLC conditions can be used to determine the chemical purity of the compounds...

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HCV NS5A Inhibitor from Theravance, Inc. to treat hepatitis C virus infection

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SERTINDOLE

.   SERTINDOLE Sertindole (brand names: Serdolect, and Serlect) is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company H. Lundbeck and marketed under license by...

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FDA approves new treatment for HIV

FDA approves new treatment for HIV 11/05/2015 12:53 PM EST The U.S. Food and Drug Administration today approved Genvoya (a fixed-dose combination tablet containing elvitegravir, cobicistat,...

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SCYX 7158

SCYX-7158 SCYX-7158 [4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydro-benzo[c]oxaborol-6-yl-2-trifluoromethyl benzamide]...

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This blog New Drug Approvals will touch 10 lakh views soon……..as on 7 NOV 2015

This blog New Drug Approvals will touch 10 lakh views soon……..as on 7 NOV 2015 http://newdrugapprovals.org/       ////////Filed under: Anthony crasto, BLOGS Tagged: BLOG, New drug approvals

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CEP 18770, Delanzomib

CEP-18770, Delanzomib cas 847499-27-8 Chemical Formula: C21H28BN3O5 Exact Mass: 413.21220, UNII-6IF28942WO; CT-47098 NPH 007098 NPH007098...

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SILICO LINEZOLID

Therapeutic options for brain infections caused by pathogens with a reduced sensitivity to drugs are limited. Recent reports on the potential use of linezolid in treating brain infections prompted us...

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New route for Expensive drug Ivacaftor synthesis from CSIR-NCL, Pune, India

IVACAFTOR   Breaking and Making of Rings: A Method for the Preparation of 4-Quinolone-3-carb­oxylic Acid Amides and the Expensive Drug Ivacaftor N. Vasudevan†, Gorakhnath R. Jachak† and D. Srinivasa...

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GKM 001 in pipeline for Diabetes by Advinus

  GKM 001……Several probables Watch out on this post as I get to correct structure……….. Advinus Therapeutics Private L, A glucokinase activator for treatment of type II diabetes Company Advinus...

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ZYDPLA 1 From ZYDUS CADILA, a new NCE in Gliptin class of antidiabetic agents.

GENERAL STRUCTURE ZYDPLA 1……….Probable Representative structure only, I will modify it as per available info Cadila Healthcare Limited ZYDPLA1 is an orally active, small molecule NCE, discovered and...

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DC_AC50, selective way of blocking copper transport in cancer cells

    DC_AC50 3-amino-N-(2-bromo-4,6-difluorophenyl)-6,7-dihydro-5H- cyclopenta [b] thieno [3,2-e] pyridine-2-carboxamide licensed DC_AC50 to Suring Therapeutics, in Suzhou, China INNOVATORS  Jing Chen...

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Zydus Cadila’s new 2-phenyl-5-heterocyclyl-tetrahydro-2h-pyran-3-amine...

List of compounds as DPP-IV inhibitors Watch out on this post as I get to correct structure……….. 2-phenyl-5-heterocyclyl-tetrahydro-2h-pyran-3-amine compounds   One Example of...

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EV 077

EV-077 SER  150 (formerly EV-077) Also known as: formerly EV-077-3201 EV-077-3201-2TBS CAS 1384128-29-3 Evolva INNOVATOR Evolva Sa Oral thromboxane receptor antagonist and thromboxane synthase...

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