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LIK 066, Novartis, for the treatment of type 2 diabetes
LIK-066, a new flozin on the horizon C23 H28 O7 . 2 C6 H11 N O, 642.7795, 1 :2 co-crystal of Example 62 : L-proline. A melting point 176°C…WO2011048112 CAS 1291095-45-8,...
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AZD 1080
. AZD 1080 2-Hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile AZD1080 is a selective, orally active,...
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New...
CAS 1452582-16-9, 428.47, C23 H26 F2 N4 O2 1H-Indazole-3-carboxamide, 5-(2,3-difluorophenyl)-N-[[1-(2-methoxyethyl)-4-piperidinyl]methyl]- Aziende Chimiche Riunite Angelini Francesco...
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AMG-319
AMG-319 N-((1S)-1-(7-fluoro-2-(2-pyridinyl)-3-quinolinyl)ethyl)-9H-purin-6-amine, WO2008118468 (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine CAS 1608125-21-8 Chemical...
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4′-((5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazol-2-yl-thio)-methy...
Cas 1820758-44-8 C24 H18 F N3 O4 S 4′-((5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazol-2-yl-thio)-methyl)-4-fluorobiphenyl-2-carboxamide Glycogen synthase kinase-3 (GSK-3) is a...
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USP revises Chapter on Pharmaceutical Water
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Changes to the fundamental monograph on pharmaceutical water <1231> Water for Pharmaceutical Purposes from the US-American...
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Mirogabalin
Mirogabalin, A-2000700, DS-5565 1138245-13-2, C12H19NO2, 209.28 [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid...
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Zydus gets USFDA nod for clinical trials of Saroglitazar
November 19, 2015 New Delhi: Zydus Cadila has received US health regulator’s nod to initiate phase II clinical trials of Saroglitazar, its new drug for treating high fat levels in body due to...
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Atagabalin
Atagabalin Trans-dimethyl gababutin; UNII-JT7957Q2FB; 223445-75-8; 2-[(3S,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl]acetic acid DNC014878 AN-5147 PD-0200390 D09581...
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Experimental Study on Holoptelia Integrifolia Planch. in Relation to Diabetes...
Holoptelia integrifolia (Chirabilva) Experimental Study on Holoptelia Integrifolia in Relation to Diabetes Mellitus Type 2 International Journal of Pharma Research &Review,Sept2015; 4(9):21-25...
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WCK 2349 in phase II trials by Wockhardt
. CH3SO3H WCK 2349 Cas 948895-94-1 methane sulfonate Base..706809-20-3 527.563., C22 H26 F N3 O5 . C H4 O3 S...
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WCK 5107 in PHASE 1 FROM WOCKHARDT
WCK 5107 Wockhardt Limited Useful for treating bacterial infections CAS 1436861-97-0 disclosed in PCT International Patent Application No. PCT/IB2012/054290D trans- sulphuric acid...
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New molecules from Wochkardt to treat bacterial infections
WCK ? ( Not sure) Keep watching this post……….. TRANS-SULFURIC ACID MONO-{2-[5-(3-AZETIDINYLAMINO)-METHYL-[1,3,4]- OXADIAZOL-2-YL]-7-OXO-1,6-DIAZABICYCLO[3.2.1] OCT-6-YL} ESTER TRIFLUOROACETATE...
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WCK Series by Wockhardt for treating the bacterial infection
Which WCK is it, WCK-4873 , WCK-4086, WCK ? for treating the bacterial infection. (Not sure) will arrive at correct one….keep watching……….. CAS 1627163-98-7 BASE : 1174020-25-7 C14 H16 N2 O4 . Na,...
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Flow Chemistry India 2016, 21-22 January 2016, Mumbai, India
Flow Chemistry India 2016 Date: Thursday, 21 January 2016 – Friday, 22 January 2016 Location: Mumbai, India SELECTBIO INDIA...
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New Antibacterial oxazolidinones in pipeline by Wockhardt
WCK ? (5S)-N-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (5S)-N- {3-[3,5-difluoro-4-(4-hydroxy-(4-methoxymethyl)-piperidin-...
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Revised USP Chapter on Visual Inspection published
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: After the long-awaited Chapter <1790> on visual inspection of injections was first published in the PF 41(1) as a draft the USP has...
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TARANABANT
Taranabant ( MK-0364) 701977-09-5 N-[3-(4-Chlorophenyl)-2(S)-(3-cyanophenyl)-1(S)-methylpropyl]-2-methyl-2-[5-(trifluoromethyl)pyridin-2-yloxy]propionamide...
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Pfizer’s PF 04937319 glucokinase activators for the treatment of Type 2 diabetes
PF 04937319 N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide MW 432.43 MF C22 H20 N6 O4 CAS 1245603-92-2 2-Pyrimidinecarboxamide,...
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Pfizer’s PF 04991532 a Hepatoselective Glucokinase Activator Clinical...
PF 04991532 GKA PF-04991532 (S)-6-{3-cyclopentyl-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propanamido}nicotinic acid (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic...
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