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Channel: DR ANTHONY MELVIN CRASTO Ph.D – New Drug Approvals
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Dostarlimab

(Heavy chain)EVQLLESGGG LVQPGGSLRL SCAASGFTFS SYDMSWVRQA PGKGLEWVST ISGGGSYTYYQDSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCASPY YAMDYWGQGT TVTVSSASTKGPSVFPLAPC SRSTSESTAA LGCLVKDYFP EPVTVSWNSG ALTSGVHTFP...

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ZyCoV-D

ZyCoV-D CAS 2541524-47-2  DNA vaccine construct encoding a spike protein antigen of SARS-CoV-2 virus (Zydus-Cadila)...

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Loncastuximab tesirine

Loncastuximab tesirine ZYNLONTA FDA APPROVED 2021/4/23 FormulaC6544H10048N1718O2064S52Exact mass147387.9585CAS1879918-31-6EfficacyAntineoplasitc, Anti-CD19 antibody  DiseaseDiffuse large B-cell...

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Idecabtagene vicleucel

Idecabtagene vicleucel CAS 2306267-75-2 STN: BLA 125736 An autologous T lymphocyte-enriched cell transduced ex vivo with an anti-BCMA CAR lentiviral vector encoding a chimeric antigen receptor CAR,...

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OCID 5090, Enmetazobactam

OCID 5090 Enmetazobactam Beta-lactamase inhibitor. AAI-101RN: 1001404-83-6UNII: 80VUN7L00C Molecular Formula, C11-H14-N4-O5-S, Molecular Weight, 314.3206...

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Casirivimab

(Heavy chain)QVQLVESGGG LVKPGGSLRL SCAASGFTFS DYYMSWIRQA PGKGLEWVSY ITYSGSTIYYADSVKGRFTI SRDNAKSSLY LQMNSLRAED TAVYYCARDR GTTMVPFDYW GQGTLVTVSSASTKGPSVFP LAPSSKSTSG GTAALGCLVK DYFPEPVTVS WNSGALTSGV...

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Imdevimab

(Heavy chain)QVQLVESGGG VVQPGRSLRL SCAASGFTFS NYAMYWVRQA PGKGLEWVAV ISYDGSNKYYADSVKGRFTI SRDNSKNTLY LQMNSLRTED TAVYYCASGS DYGDYLLVYW GQGTLVTVSSASTKGPSVFP LAPSSKSTSG GTAALGCLVK DYFPEPVTVS WNSGALTSGV...

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PTX-COVID19-B

PTX-COVID19-B mRNA-based vaccine Providence Therapeutics; Canadian government bioRxiv (2021), 1-50. https://www.biorxiv.org/content/10.1101/2021.05.11.443286v1 Safe and effective vaccines are needed...

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Ibrexafungerp citrate

Ibrexafungerp citrate アイブレキサフンジェルプクエン酸塩; FormulaC44H67N5O4. C6H8O7cas1965291-08-0free 1207753-03-4Mol weight922.1574 Brexafemme, fda approved 2021, 2021/6/1 Antifungal, Cell wall biosynthesis...

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Corbevax, BioE COVID-19, BECOV2D

Corbevax BioE COVID-19, BECOV2D the Baylor College of Medicine in Houston, United States, Dynavax Technologies Adjuvanted protein subunit vaccine Corbevax is a “recombinant protein sub-unit” vaccine,...

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Infigratinib phosphate

Infigratinib phosphate FDA APPR Truseltiq 2021/5/28 インフィグラチニブリン酸塩; 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-[6-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]-1-methylurea;phosphoric acid BGJ...

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TROPIFEXOR

TROPIFEXOR トロピフェクサー;  PHASE 2, NASH, PBC, liver fibrosis, bile acid diarrhea, non-alcoholic fatty liver disease FormulaC29H25F4N3O5SCAS1383816-29-2Mol weight603.5845 TROPIFEXORLJN...

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Sotorasib

Sotorasib 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one AMG 510AMG-510AMG510...

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Pegcetacoplan

Sequence: 1ICVWQDWGAH RCTXK Sequence: 1ICVWQDWGAH RCTXK Sequence Modifications TypeLocationDescriptionterminal mod.Lys-15C-terminal amideterminal mod.Lys-15′C-terminal amidebridgeCys-2 –...

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Amivantamab

(A chain)QVQLVESGGG VVQPGRSLRL SCAASGFTFS TYGMHWVRQA PGKGLEWVAV IWDDGSYKYYGDSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARDG ITMVRGVMKD YFDYWGQGTLVTVSSASTKG PSVFPLAPSS KSTSGGTAAL GCLVKDYFPE PVTVSWNSGA...

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Piflufolastat F 18 injection, Dcfpyl F-18

Piflufolastat F 18 injection Dcfpyl F-18 CAS 207181-29-0 PLAIN F 1423758-00-2  WITHOUT RADIO LABELC18 H23 F N4 O8, 441.4L-Glutamic acid,...

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Colchicine

Colchicine CAS Registry Number: 64-86-8CAS Name:N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamideMolecular Formula: C22H25NO6Molecular Weight: 399.44 CSIR-Laxai...

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Samidorphan

Samidorphan サミドルファン; FormulaC21H26N2O4CAS852626-89-2Mol weight370.4421 FDA  APPROVED 5/28/2021 Lybalvi ALKS 33ALKS-33RDC-0313RDC-0313-00 Product Ingredients UNII0AJQ5N56E0 CAS Number1204592-75-5...

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Drospirenone

Drospirenone FDA APPROVED 4/15/2021, To prevent pregnancy Nextstellis New Drug Application (NDA): 214154Company: MAYNE PHARMALabel (PDF)Letter (PDF)ReviewLabel (PDF)DrospirenoneCAS Registry Number:...

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Nanatinostat

Nanatinostat Tractinostat CHR-3996, CHR 3996, VRx 3996, C20H19FN6O2, 394.41 CAS 1256448-47-1 2-[(1α,5α,6α)-6-[[(6-Fluoro-2-q...

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