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Fluorofenidone
Fluorofenidone 1- (3-fluorophenyl) -5-methyl – 2 (1H) pyridone 2(1H)-Pyridinone, 1-(3-fluorophenyl)-5-methyl- 1- (3_ fluorophenyl) -5_ methylpyridine _2 (IH) – one C12 H10 F N O, 203.2123...
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TECOVIRIMAT
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Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
Recently, application of the flow technologies for the preparation of fine chemicals, such as natural products or Active Pharmaceutical Ingredients (APIs), has become very popular, especially in...
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Merck’s Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP)
Indoline 7 as in ACS MEDCHEM LETTERS, DOI: 10.1021/acsmedchemlett.5b00404 and eg 10 as in WO2015054088 (2R)- 1,1,1 -trifluoro-3-(3-(3-(trifluoromethoxy)benzyl)-3-(3-...
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FK-3311
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Preclinical characterization of substituted...
MW 422.79, MF C18 H14 Cl F3 N6 O cas 1627748-32-6 1,2,4-Triazolo[4,3-a]pyrazin-8(5H)-one,...
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FDA gives Advice on the Use of Control Charts
see………………..http://www.gmp-compliance.org/enews_05135_FDA-gives-Advice-on-the-Use-of-Control-Charts_15093,15290,15250,15405,Z-VM_n.html In our News entitled “Statistics and Process Validation: current...
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Statistics and Process Validation: current Findings of the FDA
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What are “complex manufacturing processes”? A recent reply from the EMA
The Variations Regulation (EC) no. 1234/2008 of the European Commission defines the procedure for variations of existing marketing authorisations. The “detailed guidelines for the various categories...
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Dofequidar fumarate
Dofequidar fumarate Phase III A P-glycoprotein inhibitor potentially for the treatment of breast cancer and non-small lung cancer (NSCLC). MS-209; Dofequidar fumarate CAS No. 129716-58-1 (Dofequidar...
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AZD 2716
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BMS 955829
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Shanghai Hengrui’s potent inhibitors of Human Uric Acid Transporter 1 (hURAT1)
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New Patent from Zydus Cadila, Canagliflozin, US 20160002275
US-20160002275 CADILA HEALTHCARE LIMITED [IN] DESAI, Sanjay Jagdish [IN] PARIHAR, Jayprakash Ajitsingh [IN] PATEL, Jagdish Maganlal [IN] SURYAWANSHI, Uday Suresh [IN] BHALALA, Jaisukh Bhupatbhai [IN]...
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NEW PATENT, TICAGRELOR, DR. REDDY’S LABORATORIES LIMITED, WO 2016001851
WO 2016001851 DR. REDDY’S LABORATORIES LIMITED [IN/IN]; 8-2-337, Road No. 3, Banjara hills, Hyderabad, Telangana Hyderabad 500034 (IN) DAHANUKAR, Vilas; (IN). ELATI, Ravi Ram Chandrasekhar; (IN)....
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NEW PATENT, WO2016001844, SUN PHARMACEUTICALS, AFATINIB DIMALEATE
WO2016001844, AMORPHOUS FORM OF AFATINIB DIMALEATE SUN PHARMACEUTICAL INDUSTRIES LIMITED VERMA, Shyam Sunder; (IN). SINGH, Shravan Kumar; (IN). SINGH, Kaptan; (IN). PRASAD, Mohan; (IN) Afatinib...
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Continuous ruthenium-catalyzed methoxycarbonylation with supercritical carbon...
Catal. Sci. Technol., 2016, Advance Article DOI: 10.1039/C5CY01883H, Paper Stefan Christiaan Stouten, Timothy Noel, Qi Wang, Matthias Beller, Volker Hessel The methoxycarbonylation of cyclohexene...
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New patent, WO 2016001885, Dr Reddy’s Laboratories Ltd, Eliglustat hemitartarate
WO 2016001885 DR. REDDY’S LABORATORIES LIMITED [IN/IN]; 8-2-337, Road No. 3, Banjara Hills, Telangana, India Hyderabad 500034 (IN) VELAGA, Dharma Jagannadha Rao; (IN). PEDDY, Vishweshwar; (IN). VYALA,...
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SKLB 1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl,
SKLB 1028 IND Filed A multi-targeted inhibitor potentially for the treatment of leukemia and non small cell lung cancer. SKLB-1028 Si Chuan University, 四川大学 CAS 1350544-93-2...
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Acotiamide
Acotiamide hydrochloride trihydrate CAS#: 773092-05-0 (Acotiamide HCl hydrate, 1:1:3); 185104-11-4(Acotiamide HCl, 1:1); 185106-16-5 (Acotiamide free base) Chemical Formula: C21H37ClN4O8S...
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