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Specific Stereoisomeric Conformations Determine the Drug Potency of...
Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.8b00565 Pronay Das, Palak Babbar,...
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GFT 505
(E)-Elafibranor Molecular FormulaC22H24O4S Average mass384.489 Da Elafibranor CAS 824932-88-9 E Z MIXTURE USAN CAS 923978-27-2 E ISOMER INN...
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Selonsertib, GS-4997, GS-4977
GS-4997, GS-4977, Selonsertib Selonsertib; 1448428-04-3; GS-4997; UNII-NS3988A2TC; NS3988A2TC;...
View ArticleFDA approves new treatment Xeljanz (tofacitinib) for moderately to severely...
FDA approves new treatment for moderately to severely active ulcerative colitis The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with...
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Lofexidine, лофексидин , لوفيكسيدين , 洛非西定 ,
Lofexidine Molecular FormulaC11H12Cl2N2O Average mass259.132 Da (±)-2-[1-(2,6-Dichlorophenoxy)ethyl]-2-imidazoline UNII:UI82K0T627 лофексидин [Russian] [INN] لوفيكسيدين [Arabic] [INN] 洛非西定 [Chinese]...
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Tildrakizumab-asmn
Heavy chain: QVQLVQSGAEVKKPGASVKVSCKASGYIFITYWMTWVRQAPGQGL EWMGQIFPASGSADYNEKFEGRVTMTTDTSTSTAYMELRSLRSDD TAVYYCARGGGGFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTS GGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYS...
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ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals...
TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.ONC201 was originally identified as a small molecule that...
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Nitisinone, ニチシノン
Nitisinone ニチシノン Orfadin Launched – 2002, NTBC SC-0735 SYN-118 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione 2-(2-Nitro-4-trifluoromethylbenzoyl)cyclohexane-1,3-dione...
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Burosumab-twza, ブロスマブ
> Burosumab Heavy Chain Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTNHYMHWVRQAPGQGLEWMGIINPISGSTSN AQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARDIVDAFDFWGQGTMVTVSSAST...
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PF-06409577
PF-06409577 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid CAS Number 1467057-23-3, C19H16ClNO3, 341.79 Biochem/physiol Actions PF-06409577 is a potent and selective activator...
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Doxepin, ドキセピン
Doxepin 1668-19-5 1229-29-4 (hydrochloride), 4698-39-9 ((E)-isomer); 25127-31-5 ((Z)-isomer) Launched – 1964 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl- 1-Propanamine,...
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YINLITINIB
YINLITINIB error EMAIL ME amcrasto@gmail.com (E)-4-[(4aR,7aS)-2,3,4a,5,7,7a-hexahydro-[1,4]dioxino[2,3-c]pyrrol-6-yl]-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]but-2-enamide...
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FDA approves first biosimilar to Neulasta, Fulphila (pegfilgrastim) to help...
FDA approves first biosimilar to Neulasta to help reduce the risk of infection during cancer treatment The U.S. Food and Drug Administration today approved Fulphila (pegfilgrastim-jmdb) as the first...
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Carglumic acid, карглумовая кислота , حمض كاروغلوميك , カルグルミ酸 ,
Carglumic acid N-Carbamyl-L-glutamate; Molecular FormulaC6H10N2O5 Average mass190.154 Da N-Carbamylglutamate карглумовая кислота [Russian] [INN] حمض كاروغلوميك [Arabic] [INN] カルグルミ酸; 1188-38-1 [RN]...
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Penciclovir
Penciclovir Molecular FormulaC10H15N5O3 Average mass253.258 Da Cas 39809-25-1 97845-62-0 (Na salt) Launched – 1996 PERRIGO, Herpes labialis...
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FDA and USDA announce key step to advance collaborative efforts to streamline...
DRUG REGULATORY AFFAIRS INTERNATIONAL FDA and USDA announce key step to advance collaborative efforts to streamline produce safety requirements for farmers As part of the U.S. Food and Drug...
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Isavuconazonium sulfate, Изавуконазониев сулфат
Isavuconazonium sulfate Изавуконазониев сулфат CAS 946075-13-4 MOLECULAR FORMULA: C35H36F2N8O9S2 MOLECULAR WEIGHT: 814.837 g/mol BAL-8557-002, BAL 8557...
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VORAPAXAR SULPHATE
VORAPAXAR Thrombosis, Antiplatelet Therapy, PAR1 Antagonists , MERCK ..ORIGINATOR Ethyl...
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Chenodeoxycholic acid, ケノデオキシコール酸
Chenodeoxycholic acid Chenodiol Molecular FormulaC24H40O4 Average mass392.572 UNII-0GEI24LG0J ケノデオキシコール酸 474-25-9 [RN] chenodeoxycholic acid [JP15] [Wiki] (+)-chenodeoxycholic acid...
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Gadobenate Dimeglumine
Gadobenate Dimeglumine Molecular Formula: C36H62GdN5O21 Molecular Weight: 1058.156 g/mol cas 113662-23-0 FREEFORM INGREDIENT UNII CAS Gadobenate dimeglumine 3Q6PPC19PO 127000-20-8 Used in MR imaging...
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