Clik here to view.
Design and synthesis of indoline thiohydantoin derivatives based on...
4-(6-chloro-1-oxo-3-thioxo-9,9a-dihydro-1H-imidazo[1,5-a]indol-2(3H)-yl)-2-(trifluoromethyl)-benzonitrile WILL BE UPDATED……… Prostate cancer, one of the most malignant tumors worldwide, is the second...
View ArticleClik here to view.
A Concise and Highly Efficient Synthesis of Praziquantel as an Anthelmintic Drug
PAPER HETEROCYCLES An International Journal for Reviews and Communications in Heterocyclic Chemistry Web Edition ISSN: 1881-0942 Published online: 11th October, 2016 Paper | Regular issue | Prepress...
View ArticleClik here to view.
QbD: Controlling CQA of an API
DRUG REGULATORY AFFAIRS INTERNATIONAL The importance of Quality by Design (QbD) is being realized gradually, as it is gaining popularity among the generic companies. However, the major hurdle faced by...
View ArticleClik here to view.
QbD Sitagliptin
DRUG REGULATORY AFFAIRS INTERNATIONAL Application of On-Line NIR for Process Control during the Manufacture of Sitagliptin George Zhou*, Shane Grosser, Lei Sun, Gabriel Graffius, Ganeshwar Prasad,...
View ArticleClik here to view.
BOSENTAN PRECURSOR
N,N′-(6,6′-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis- (methylene)bis(oxy)bis(5-(2-methoxy phenoxy)-2,2′-bipyrimidine-6,4-diyl))bis(4-tert-butylbenzenesulfonamide) Mp: 72−74 °C. 1 H NMR (400 MHz,...
View ArticleClik here to view.
BMS-599793
BMS-599793 (DS003, BMS-599793) Molecular Formula: C27H22N6O3 Molecular Weight: 478.512 g/mol...
View ArticleClik here to view.
Solifenacin, солифенацин , سوليفيناسين , 索利那新 ,
SOLIFENACIN, YM-905 MF C23H26O2, a molecular weigt 362.4647 CAS 242478-37-1 солифенацин [Russian] سوليفيناسين [Arabic] 索利那新 [Chinese] 242478-37-1 (Solifenacin ) 242478-38-2 (Solifenacin Succinate)...
View ArticleClik here to view.
Rush , few seats, ACS INDUSTRY SYMPOSIUM RECENT ADVANCES IN DRUG DEVELOPMENT...
ACS INDUSTRY SYMPOSIUM RECENT ADVANCES IN DRUG DEVELOPMENT IN PARTNERSHIP WITH DR. REDDY’S LABORATORIES HYDERABAD, INDIA 11-12 NOVEMBER 2016 click http://acssymposium.org.in/ for...
View ArticleClik here to view.
PF 610355 Revisited
PF-610355 Molecular Formula C34H39N3O6S Average mass 617.755 Da PF 610655, PF-00610355; PF-610,355...
View ArticleClik here to view.
Asymmetric synthesis of (S)-phenylacetylcarbinol – closing a gap in C–C bond...
Green Chemistry International Green Chem., 2017, Advance ArticleDOI: 10.1039/C6GC01803C, Communication Torsten Sehl, Saskia Bock, Lisa Marx, Zaira Maugeri, Lydia Walter, Robert Westphal, Constantin...
View ArticleClik here to view.
Algae-mediated biosynthesis of inorganic nanomaterials as a promising route...
Green Chemistry International Green Chem., 2016, Advance ArticleDOI: 10.1039/C6GC02346K, Critical Review Si Amar Dahoumane, Mourad Mechouet, Kushlani Wijesekera, Carlos D. M. Filipe, Clemence Sicard,...
View ArticleClik here to view.
BRD 2879
BRD2879 BRD-K56962879-001-01-5 CAS 1304750-47-7 Chemical Formula: C30H38FN3O5S Molecular Weight: 571.7084...
View ArticleClik here to view.
Metal-free annulation/aerobic oxidative dehydrogenation of cyclohexanones...
Green Chemistry International Green Chem., 2016, Advance ArticleDOI: 10.1039/C6GC02396G, Communication Gopal Chandru Senadi, Ganesh Kumar Dhandabani, Wan-Ping Hu, Jeh-Jeng Wang We have identified...
View ArticleClik here to view.
PF 06273340
PF-06273340 N-(5-(2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide CAS 1402438-74-7 Chemical Formula: C23H22ClN7O3...
View ArticleClik here to view.
Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK...
(-)-32 as an off-white solid. Analytical data LCMS 418 [M+H]+1 H NMR (400 MHz, DMSO-d6) δ 8.23 (s, 1H), 6.88 (d, J = 8.0 Hz, 1H), 6.68 (s, 1H), 6.61 (dd,J = 11.2, 2.0 Hz, 1H), 6.49-6.38 (m, 2H), 6.33...
View ArticleClik here to view.
ENHANCED ANALYTICAL METHOD CONTROL STRATEGY CONCEPT
DRUG REGULATORY AFFAIRS INTERNATIONAL ENHANCED ANALYTICAL METHOD CONTROL STRATEGY CONCEPT The benefits of quality by design (QbD) concepts related to both product (ICH Q8)1 and drug substance (ICH...
View ArticleClik here to view.
Зопиклон , Zopiclone, زوبيكلون , 佐匹克隆
ZOPICLONE зопиклон زوبيكلون 佐匹克隆 (±)-Zopiclone 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester 256-138-9 [EINECS] 43200-80-2 [RN]...
View ArticleClik here to view.
Valdetamide
CAS Registry Number: 512-48-1 CAS Name: 2,2-Diethyl-4-pentenamide Additional Names: diethylallylacetamide Trademarks: Novonal (Hoechst) Molecular Formula: C9H17NO Molecular Weight: 155.24 Percent...
View ArticleClik here to view.
Acetylcholine Chloride
Acetylcholine Chloride 2-acetyloxyethyl(trimethyl)azanium;chloride 60-31-1 Molecular Formula: C7H16ClNO2 Molecular Weight: 181.66 g/mol Acetylcholine chloride is obtained as white or off-white...
View ArticleClik here to view.
New EDQM’s Public Document informs about the Details required in a New CEP...
DRUG REGULATORY AFFAIRS INTERNATIONAL A Policy Document recently published by the EDQM describes regulations for referencing already existing CEPs in an application for a new CEP. Read more about how...
View Article