CAS Registry Number: 512-48-1
CAS Name: 2,2-Diethyl-4-pentenamide
Additional Names: diethylallylacetamide
Trademarks: Novonal (Hoechst)
Molecular Formula: C9H17NO
Molecular Weight: 155.24
Percent Composition: C 69.63%, H 11.04%, N 9.02%, O 10.31%
Literature References: Description: Bockmühl, Schaumann, Dtsch. Med. Wochenschr. 54, 270 (1928). Pharmacokinetics and metabolism: H. Uehleke, M. Brinkschulte-Freitas, Arch. Pharmacol. 302, 11 (1978). TLC determn in urine: E. Klug, P. Toffel, Arzneim.-Forsch. 29, 1651 (1979).
Properties: White powder, mp 75-76°. Sol in 120 parts water; freely sol in alcohol, ether.
Melting point: mp 75-76°
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Amides.
Valdetamid (Valdetamide)
Structural formula
UV – spectrum
 |
||||
| Conditions : Concentration – 50 mg / 100 ml | ||||
| The solvent designation schedule | methanol
|
Water
|
0.1 M HCl
|
0.1M NaOH
|
|---|---|---|---|---|
| maximum absorption | – | – | – | – |
 |
– | – | – | – |
| ε | – | – | – | – |
IR – spectrum
| Wavelength (μm) |
|---|
 |
| Wave number (cm -1 ) |
| Range | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
 |
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| 10 largest peaks: | ||||||||||
| Peak | 53 | 55 | 57 | 67 | 69 | 81 | 112 | 126 | 127 | 140 |
| Value | 152 | 848 | 115 | 141 | 929 | 156 | 286 | 999 | 338 | 238 |
References
-
UV and IR Spectra. H.-W. Dibbern, RM Muller, E. Wirbitzki, 2002 ECV
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NIST / EPA / NIH Mass Spectral Library 2008
-
Handbook of Organic Compounds. NIR, IR, Raman, and UV-Vis Spectra Featuring Polymers and Surfactants, Jr., Jerry Workman.Academic Press, 2000.
-
Handbook of ultraviolet and visible absorption spectra of organic compounds, K. Hirayama. Plenum Press Data Division, 1967.
Brief background information
| Salt | ATC | Formula | MM | CAS |
|---|---|---|---|---|
| – | N05C | C 9 H 17 NO | 155.24 g / mol | 512-48-1 |
Using
-
hypnotic
Classes substance
-
Amides
Synthesis Way
| Synthesis of a) |
|---|
|
Trade names
| A country | Tradename | Manufacturer |
|---|---|---|
| Germany | Arantxa | Hoechst |
| Betadorm-H | Woelm | |
| insomnia | ICN | |
| Nokturetten | Starke | |
| New Dolestan | Much | |
| Ukraine | no | no |
Formulations
-
dragees 50 mg;
-
300 mg Tablets
References
-
DRP 473 329 (IG Farben; appl 1925.).
-
DRP 616 876 (IG Farben; appl 1930.).
-
DRP 622 875 (IG Farben; appl 1931.).
-
GB 253,950 (IG Farben; appl 1926;.. D-prior 1925).
1H NMR PREDICT
13C NMR PREDICT
Filed under: Uncategorized Tagged: Valdetamide
