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Channel: DR ANTHONY MELVIN CRASTO Ph.D – New Drug Approvals
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Imidafenacin, イミダフェナシン

Imidafenacin イミダフェナシン Cas 170105-16-5 C20H21N3O, 319.408 APPROVED JAPAN 2015-07-29 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide 4-(2-methylimidazol-1-yl)-2,2-di(phenyl)butyramide D06273...

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Ranolazine

Ranolazine 雷诺嗪 MF C24H33N3O4 MW 427.536 Sponsor/Developer: Gilead Mechanism of action: Late sodium current inhibitor Indication (Phase): Type 2 diabetes (Phase III) A Phase 3 Study of Ranolazine in...

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FDA grants accelerated approval to first drug for Duchenne muscular dystrophy

CAS 1173755-55-9 eteplirsen, eteplirsén [Spanish], étéplirsen [French] , eteplirsenum [Latin], этеплирсен [Russian], إيتيبليرسان [Arabic] Structure credit...

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Pimavanserin

Pimavanserin MF C25H34FN3O2 MW 427.555 Pimavanserin, ACP 103, ACP-103; BVF-048 N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N’-(4-(2-methylpropyloxy)phenylmethyl)carbamide, 706779-91-1...

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FDA approves Amjevita, a biosimilar to Humira

FDA approves Amjevita, a biosimilar to Humira The U.S. Food and Drug Administration today approved Amjevita (adalimumab-atto) as a biosimilar toHumira (adalimumab) for multiple inflammatory diseases....

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WO 2016147120, AZILSARTAN, NEW PATENT, SMILAX Laboratories Ltd

WO-2016147120, AZILSARTAN, NEW PATENT, SMILAX Laboratories Ltd SMILAX LABORATORIES LIMITED [IN/IN]; Plot No. 12/A, Phase – III, I.D.A. Jeedimetla, Hyderabad 500 055 (IN). The present invention relates...

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WO 2016147197, DAPAGLIFLOZIN, NEW PATENT, HARMAN FINOCHEM LIMITED

WO 2016147197, DAPAGLIFLOZIN, NEW PATENT, HARMAN FINOCHEM LIMITED LINK>>> (WO2016147197) A NOVEL PROCESS FOR PREPARING (2S,3R,4R,5S,6R)-2-[4-CHLORO-3-(4-ETHOXYBENZYL)PHENY 1] -6-(HY DROXY...

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VT 1129

VT 1129 1340593-70-5 CAS MF C22 H14 F7 N5 O2, MW 513.37 2-Pyridineethanol, α-(2,4-difluorophenyl)-β,β-difluoro-α-(1H-tetrazol-1-ylmethyl)-5-[4-(trifluoromethoxy)phenyl]-, (αR)- R ISOMER ROTATION +...

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Synthesis of 4-Heteroaryl–Quinazoline Derivatives as Potential Anti-breast...

Ethyl 2-[(6,7-dimethoxyquinazolin-4-yl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate (15b) Yield: 76%; mp: 254–256°C; IR (cm−1): 3200 (NH), 2974, 2854 (CH-aliphatic), 1656 (C=O);...

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Photoinduced Conversion of Antimelanoma Agent Dabrafenib to a Novel...

N-(5-amino-2-tert-butyl)-11-fluorbenzol[f]thiazol-[4,5-h]-quinazolin-10-yl)-2,6-difluorbenzolsulfonamide = Dabrafenib_photo (2) C23H18F3N5O2S2 (Mr = 517.09) Solution of 5 mg (9.6 μmol) dabrafenib in 2...

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Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist from...

(S)-3-(4-((3-((isopropyl(thiophen-3- ylmethyl)amino)methyl)benzyl)oxy)phenyl)hex-4-ynoic acid Calcium (S)-3-(4-((3-((isopropyl(thiophen-3-yl methyl)amino)methyl)benzyl)oxy)phenyl)hex-4-ynoate Calcium...

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Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain from...

2-(2-(1H-1,2,3-triazol-5-yl)ethoxy)-1-(2-((2,3-dihydro-1H-inden-2-yl)amino)-5,7-dihydro-6Hpyrrolo[3,4-d]pyrimidin-6-yl)ethan-1-one l-[2-(2,3-dihydro- lH-inden-2-ylamino)-5,7-dihydro-6H-pyrrolo[3,4-...

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Green Solvent – A sustainable option – Dr. Denis Prat, SANOFI, France

Green Chemistry International Dr. Denis Prat Head of Process Safety & Automated Chemistry Chemistry & Biotechnology Development, SANOFI, France Green Solvent – A sustainable option – Dr. Denis...

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Consumption of a bioactive compound from Neem plant could significantly...

(From left to right) Principal Investigator Associate Professor Gautam Sethi and NUS PhD candidate Ms Zhang Jingwen from the Department of Pharmacology at the NUS Yong Loo Lin School of Medicine led a...

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Identifying “green chemistry” industrialisation barriers through case-studies

Green Chemistry International Nitesh Mehta Convenor of Industrial Green Chemistry World and Founder – Director of Newreka Green Synth Technologies Pvt Ltd nitesh.mehta@newreka.co.in Identifying “green...

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GNE-272

GNE-272 (S)-1-(3-((2-fluoro-4-(1-methyl-1H-pyrazol-4- yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin- 5(4H)-yl)ethanone...

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Clenbuterol

Clenbuterol Clenbuterol hydrochloride, NAB-365, Siropent Clenbuterol, marketed as Dilaterol, Spiropent, Ventipulmin,[1] is a sympathomimetic amine used by sufferers of breathing disorders as a...

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Tedatioxetine Revisited

Tedatioxetine TEDATIOXETINE; UNII-5H681S8O3S; Lu AA24530; 508233-95-2; Molecular Formula: C18H21NS Molecular Weight: 283.43104 g/mol 4-{2-[(4-Méthylphényl)sulfanyl]phényl}pipéridine 508233-95-2 [RN]...

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VADADUSTAT

VADADUSTAT AKB-6548, PG-1016548 PG1016548, UNII:I60W9520VV, B-506 CAS 1000025-07-9 [5-(3-chlorophenyl)-3-hydroxypyridine-2-carboxamido]acetic acid...

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Glecaprevir (ABT-493)

Glecaprevir (ABT-493), A-1282576.0...

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