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HNIW, CL 20, 六硝基六氮杂异伍兹烷

  HNIW, CL-20 Molecular FormulaC6H6N12O12 Average mass438.185 Da 1,3,4,7,8,10-hexanitrooctahydro-1H-5,2,6-(epiminomethanetriylimino)imidazo[4,5-b]pyrazine CAS 135285-90-4 Hexanitrohexaazaisowurtzitane...

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FDA approves first subcutaneous C1 Esterase Inhibitor to treat rare genetic...

FDA approves first subcutaneous C1 Esterase Inhibitor to treat rare genetic disease 06/22/2017   The U.S. Food and Drug Administration today approved Haegarda, the first C1 Esterase Inhibitor (Human)...

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Lisdexamphetamine

Lisdexamfetamine Molecular FormulaC15H25N3O Average mass263.379 Da 608137-32-2 [RN] Elvanse [Trade name] Hexanamide, 2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl]-, (2S)- Lisdexamfetamine...

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Imigliptin dihydrochloride, Xuanzhu Pharma Co Ltd, NEW PATENT, WO 2017107945

Imigliptin dihydrochloride, Xuanzhu Pharma Co Ltd, NEW PATENT, WO 2017107945 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2017107945&redirectedID=true Applicants: XUANZHU PHARMA...

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NEW PATENT, PONESIMOD, CRYSTAL PHARMATECH, WO 2017107972

NEW PATENT, PONESIMOD,  CRYSTAL PHARMATECH, WO 2017107972 Novel crystalline forms I, II and III of ponesimod . Useful as a selective sphingosine-1-phosphate receptor-1 (S1P1) receptor agonist, for the...

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Cp2TiCl: An Ideal Reagent for Green Chemistry?

Green Chemistry International   The development of Green Chemistry inevitably involves the development of green reagents. In this review, we highlight that Cp2TiCl is a reagent widely used in radical...

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Increasing global access to the high-volume HIV drug nevirapine through...

  Increasing global access to the high-volume HIV drug nevirapine through process intensification Green Chem., 2017, 19,2986-2991 DOI: 10.1039/C7GC00937B, Paper Jenson Verghese, Caleb J. Kong, Daniel...

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FDA approves new treatment Endari (L-glutamine oral powder) for sickle cell...

FDA approves new treatment for sickle cell disease 07/07/2017 The U.S. Food and Drug Administration today approved Endari (L-glutamine oral powder) for patients age five years and older with sickle...

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LOXO 195

LOXO-195 CAS: 2097002-61-2 Chemical Formula: C20H21FN6O Molecular Weight: 380.4274 2097002-59-8 (RS-isomer)   1350884-56-8 (R racemic) Synonym: LOXO-195; LOXO 195; LOXO195. IUPAC:...

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FDA approves Vosevi for Hepatitis C

FDA approves Vosevi for Hepatitis C 07/18/2017 The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver...

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Voxilaprevir, فوكسيلابريفير , 伏西瑞韦 , Воксилапревир

Voxilaprevir Molecular FormulaC40H52F4N6O9S Average mass868.934 Da  1535212-07-7 cas...

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GSK 2982772

CAS: 1622848-92-3 (free base),  1987858-31-0 (hydrate) Chemical Formula: C20H19N5O3 Molecular Weight: 377.404...

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GSK 2330672

GSK 2330672 GSK 672; GSK-2330672 RN: 1345982-69-5 UNII: 386012Z45S CAS: 1345982-69-5 Chemical Formula: C28H38N2O7S Molecular Weight: 546.68 Pentanedioic acid,...

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Rosiptor acetate

Rosiptor acetate CAS: 782487-29-0 (acetate)  782487-28-9 (free base) Chemical Formula: C22H39NO4 Molecular Weight: 381.557 AQX-1125; AQX 1125; AQX1125; AQX-1125 acetate; Rosiptor acetate PHASE 3 …..a...

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Eravacycline

Eravacycline http://www.ama-assn.org/resources/doc/usan/eravacycline.pdf 1-Pyrrolidineacetamide, N-[(5aR,6aS,7S,10aS)-9-(aminocarbonyl)-7-(dimethylamino)-...

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FDA approves new targeted treatment Idhifa (enasidenib)for relapsed or...

FDA approves new targeted treatment for relapsed or refractory acute myeloid leukemia 08/01/2017 The U.S. Food and Drug Administration today approved Idhifa (enasidenib) for the treatment of adult...

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Enasidenib, Энасидениб , إيناسيدينيب ,伊那尼布 ,

Enasidenib Molecular Formula C19H17F6N7O Average mass 473.375 2-Propanol,...

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Solithromycin, солитромицин , سوليثروميسين , 索利霉素 ,

Solithromycin Molecular Formula C43H65FN6O10 Average mass 845.009 Da CEM-101;OP-1068 UNII:9U1ETH79CK...

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FDA approves Mavyret (glecaprevir and pibrentasvir) for Hepatitis C

Glecaprevir Pibrentasvir FDA approves Mavyret for Hepatitis C 08/03/2017 03:06 PM EDT The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with...

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ICH Q11 Q and A Document

DRUG REGULATORY AFFAIRS INTERNATIONAL ICH Q11   Q and A Document The topic of starting materials has been a vexed topic for some period. Indeed concerns relating to lack of clarity and issues...

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