The development of Green Chemistry inevitably involves the development of green reagents. In this review, we highlight that Cp₂TiCl is a reagent widely used in radical and organometallic chemistry, which shows, if not all, at least some of the 12 principles summarized for Green Chemistry, such as waste minimization, catalysis, safer solvents, toxicity, energy efficiency, and atom economy. Also, this complex has proved to be an ideal reagent for green C–C and C–O bond forming reactions, green reduction, isomerization, and deoxygenation reactions of several functional organic groups as we demonstrate throughout the review.

Cp₂TiCl: An Ideal Reagent for Green Chemistry?

María Castro Rodríguez^†, Ignacio Rodríguez García^‡, Roman Nicolay Rodríguez Maecker^§, Laura Pozo Morales^†, J. Enrique Oltra^∥, and Antonio Rosales Martínez^*†§⊥ 

^† Department of Chemical Engineering, Escuela Politécnica Superior, University of…