Tegomil fumarate
cas 1817769-42-8
dimethyl (2E,19E)-4,18-dioxo-5,8,11,14,17-pentaoxahenicosa-2,19-diene-1,21-dioate
4-O-[2-[2-[2-[2-[(E)-4-methoxy-4-oxobut-2-enoyl]oxyethoxy]ethoxy]ethoxy]ethyl] 1-O-methyl (E)-but-2-enedioate
- 1,21-Dimethyl (2E,19E)-4,18-dioxo-5,8,11,14,17-pentaoxaheneicosa-2,19-dienedioate
- 5,8,11,14,17-Pentaoxaheneicosa-2,19-dienedioic acid, 4,18-dioxo-, 1,21-dimethyl ester, (2E,19E)-
Chemical Formula: C18H26O11
Exact Mass: 418.15
Molecular Weight: 418.395
Elemental Analysis: C, 51.67; H, 6.26; O, 42.06
SCHEME
Patent
- Method for producing monomethyl fumarate compoundsPublication Number: WO-2017108960-A1Priority Date: 2015-12-22
- Mmf-derivatives of ethyleneglycolsPublication Number: EP-3131633-A1Priority Date: 2014-04-17
- Mmf-derivatives of ethyleneglycolsPublication Number: EP-3131633-B1Priority Date: 2014-04-17Grant Date: 2020-03-04
- Mmf-derivatives of ethyleneglycolsPublication Number: US-2017029357-A1Priority Date: 2014-04-17
- MMF-derivatives of ethyleneglycolsPublication Number: US-9969674-B2Priority Date: 2014-04-17Grant Date: 2018-05-15
Ratiopharm GmbH, WO2015158817
PATENT
WO2017108960
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2017108960
Scheme 2: Synthesis of (E)-But-2-enedioic acid 2-(2-{2-[2-((E)-3-methoxycarbonyl- acryloyloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester methyl ester
Step 1: Synthesis of (Z)-But-2-enedioic acid mono-[2-(2-{2-[2-((Z)-3- carboxy-acryloyloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl] ester
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